Researchers from BCRS have successfully prefabricated a bone graft surrogate with vascular pedicle by using devitalized hypertrophic cartilage


See our new publication:

Prefabrication of a large pedicled bone graft by engineering the germ for de novo vascularization and osteoinduction.

Epple C, Haumer A, Ismail T, Lunger A, Scherberich A, Schaefer DJ, Martin I.

Biomaterials. 2018 Nov 9;192:118-127.


DBM research group leaders Peter Itin and Ivan Martin were elected to members of the Swiss Academy of Medical Sciences


The Swiss Academy of Medical Sciences (SAMS) Senate has elected Prof. Peter Itin as honorary member and Prof. Ivan Martin as member of the SAMS Senate. They will receive their certificate at the award ceremony on November 29, 2018.

The European Research Council awards Ivan Martin (DBM) and Filippo Rijli (FMI) one of the prestigious ERC Synergy Grants.


With their 5.3 Million Euro grant the interdisciplinary team led by Filippe Rijli (Friederich Miescher Institute for Biomedical Research) and Ivan Martin aims to find out whether nasal cartilage cells, which have properties of neural crest cells during development, can be used for the regeneration of intervertebral discs.

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BCRS researchers have used adult human adipose tissue as scaffolding and cellularized materials to generate a bone organ by endochondral ossification


See our new publication :

Fractionated human adipose tissue as a native biomaterial for the generation of a bone organ by endochondral ossification.

Guerrero J, Pigeot S, Müller J, Schaefer DJ, Martin I, Scherberich A.

Acta Biomater. 2018 Sep 1;77:142-154.


Blood formation: BCRS researchers engineer human bone marrow tissue


Researchers from the BCRS, in collaboration with colleagues from ETH Zurich, have developed an artificial tissue in which human blood stem cells remain functional for a prolonged period of time.

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PD Dr. Arnaud Scherberich and Prof. Dirk J Schaefer receive a SNF project grant on Bone prefabrication for osteonecrosis


PD Dr. Arnaud Scherberich is the Principal Investigator of a new Project grant from the Swiss National Science Foundation (# 179444).

Duration: 01.05.2018 - 30.04.2022

Approved amount: 670'743 CHF

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Mimicking the molecular processes occurring during embryonic cartilage formation, researchers from the BCRS succeeded in “developmentally engineering” cartilage tissue from adult human mesenchymal stromal cells.


Their findings were recently published in PNAS.

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New Publication from BCRS


New collaborative publication by members of the BCRS:

Medeiros Da Cunha CM, Perugini V, Bernegger P, Centola M, Barbero A, Guildford AL, Santin M, Banfi A, Martin I, Marsano A.  Vascular Endothelial Growth Factor Sequestration Enhances In Vivo Cartilage Formation. Int J Mol Sci. 2017 Nov 21;18(11). Pubmed.

New Publication from BCRS


New collaborative publication by members of the BCRS:

Cerino G, Gaudiello E, Muraro MG, Eckstein F, Martin I, Scherberich A, Marsano A. Engineering of an angiogenic niche by perfusion culture of adipose-derived stromal vascular fraction cells. Sci Rep 2017 Oct 27;7(1):14252. Pubmed.